Лаборатория структуры и функций митохондрий

Научно-исследовательский институт физико-химической биологии им. А.Н. Белозерского


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A mitochondria-targeted protonophoric uncoupler derived from fluorescein.

Linking decyl-triphenyl-phosphonium to fluorescein yields a fluorescent probe that accumulates in energized mitochondria, facilitates proton transfer across membranes and stimulates mitochondrial respiration. This features a mitochondria-targeted uncoupler, being of potential interest for therapeutic use against oxidative stress-related diseases.

Ссылка на pubmed